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About this item

  • Maximum Strength 40% Zinc Oxide
  • Relieves Diaper Rash in Just 12 Hours
  • Heals & Prevents Diaper Rash
  • Forms a Thick, Long-Lasting Protective Barrier
  • Pediatrician Tested, Hypoallergenic & Free of Parabens

Desitin Maximum Strength Diaper Rash Cream, 40% Zinc Oxide

Desitin  |  SKU: 10074300000715-Single
$1299
$12.99/ea
FSA/HSA eligible with a prescription (Rx) Can be bought with an FSA/HSA card, but requires a doctor's prescription. We keep this up to date, but always confirm eligibility with your health plan. Learn more

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Desitin® Maximum Strength Original Paste is a high-potency diaper rash treatment formulated for both prevention and healing. The active ingredient is 40% zinc oxide, which is the maximum allowable concentration in over-the-counter skin protectants, providing a thick barrier to seal out wetness and irritants.

Its rich, ointment-like texture allows it to adhere to skin surfaces, offering prolonged protection and relief.In clinical studies, 90% of diaper rash cases showed noticeable relief within 12 hours of use. Desitin’s formula is hypoallergenic, paraben- and phthalate-free, and tested by pediatricians.

The paste can also double as a preventive barrier when applied before extended wear of diapers. Be aware: it may stain textiles due to its richness.

What is the active ingredient?
Zinc oxide 40%, a skin protectant.
What does it do?
It treats and helps prevent diaper rash by forming a barrier and soothing irritated skin.
Is it safe for daily use?
Yes, its hypoallergenic formula is designed for frequent use.
How long does it protect?
It is clinically shown to provide protection up to 12 hours.
Does it contain parabens or phthalates?
No—it is free of parabens, phthalates, and dyes.
Can it stain clothes?
Yes, due to its thick, rich formulation.
How do I apply it?
Cleanse and dry the diaper area; apply liberally at each diaper change, especially before extended wear.
Are there precautions or warnings?
For external use only; avoid eye contact; discontinue use if condition worsens or persists longer than 7 days; keep out of reach of children.
FSA/HSA EligibleYes, with Rx
FormCream, Paste
Active IngredientZinc Oxide, Aloe, Vitamin E
Volume4 oz
ScentScented
ApplicationDiaper Rash Treatment
PackagingTube
BrandDesitin
SKU10074300000715-Single
UPC74300000718

Key Features

  • 40% Zinc Oxide Maximum Legal Strength – Highest allowed OTC concentration for maximum efficacy
  • Rich, Thick Barrier Formula – Stays in place to seal out moisture
  • Hypoallergenic, Paraben- & Phthalate-Free – Gentle on sensitive skin
  • Up to 12-Hour Protection – Long-lasting relief and coverage
  • Clinically Demonstrated Relief – 90% of rashes improve within 12 hours
  • Can Be Used Preventively – Apply before extended diaper wear

Customers say

Customers are pleased with the efficiency and thickness of the product. They appreciate its timely delivery and its ability to perform as expected.

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