Two-Piece Pouches

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  • Coloplast SenSura Mio Flex EasiClose 2-Piece Opaque Ostomy Pouch, Drainable, Full-Circle Filter, Gray, Maxi Length, 1 3/8" Coupling, Non-Sterile, Box of 10

    Regular price $3599
    Unit price$3.60/ea
    $3060 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Full-Circle Anti-Ballooning Filter
    • Discreet Flat-Profile Design
    • Convenient Inspection Window
    • Wide EasiClose Drainage Outlet
    • Color-Matched Secure Coupling
    View details
  • SenSura Mio Two-Piece Ostomy Pouch, Drainable, Transparent, Maxi Length

    Regular price $699
    Unit price$6.99/ea
    $595 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Easy-Drain Wide Outlet
    • Maxi 655 mL Capacity
    • Flexible, Secure Adhesive
    • Quick Click Coupling
    • Full-Circle Odor Filter
    View details
  • Coloplast SenSura Mio Click Two-Piece Urostomy Pouch, Flat, Maxi Length, Drainable, Opaque

    Regular price $699
    Unit price$6.99/ea
    $595 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Secure, Move-With-You Fit
    • Soft, Fabric-Like Comfort
    • Stays Dry After Showering
    • Easy-Empty Drainable Pouch
    • Color-Coded Secure Coupling
    View details
  • ConvaTec Esteem Synergy+ Two-Piece Drainable Ostomy Pouch, Transparent, 12" Length, Box of 10

    Regular price $4699
    Unit price$4.70/ea
    $3995 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    Very low stock (6 units)
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Secure Foam Adhesive Coupling
    • Odor-Reducing Advanced Filter
    • Soft, Quiet, Water-Resistant Material
    • Convenient Bottom Drainage
    • Clear Design for Easy Monitoring
    View details
  • ConvaTec Esteem Synergy+ Ostomy Pouch One-Piece Drainable, 12" Length, 1 3/8" Stoma, Box of 10

    Regular price $4799
    Unit price$4.80/ea
    $4080 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    Low stock (7 units)
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Adhesive Coupling Technology for a secure fit
    • One-piece design with two-piece flexibility
    • Filter reduces clogging and odor
    • Soft, quiet, water-resistant material
    • Easy bottom drainage
    View details
  • ConvaTec Natura Two-Piece Ostomy Pouch, Closed End, 8", Box of 30

    Regular price $6899
    Unit price$2.30/ea
    $5865 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Secure Two-Piece Attachment
    • Quick, Mess-Free Pouch Changes
    • Discreet, Reliable Daily Wear
    • Convenient Box of 30 Supply
    • Trusted ConvaTec Natura Compatibility
    View details
  • ConvaTec Natura + Two-Piece Closed Pouch, 8", Box of 30

    Regular price $7299
    Unit price$2.43/ea
    $6205 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Secure Two-Piece Coupling
    • Discreet Closed-End Design
    • Skin-Friendly Comfort
    • Odor-Barrier Protection
    • Convenient Box of 30
    View details
  • ConvaTec Natura+ Two-Piece Tail Closure Drainable Ostomy Pouch, Transparent, 70mm Flange, 12", Box of 10

    Regular price $4499
    Unit price$4.50/ea
    $3825 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Skin-Friendly Two-Piece Design
    • Audible Secure-Click Coupling
    • Easy InvisiClose Drainage
    • Anti-Clog, Low-Noise Film Layer
    • Clear View for Easy Monitoring
    View details
  • ConvaTec Natura+ Two-Piece Ostomy Pouch, Drainable, 12", Box of 10

    Regular price $3699
    Unit price$3.70/ea
    $3145 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Secure 12-Inch Two-Piece Fit
    • Quick Snap-On Flange
    • Transparent or Opaque Options
    • Skin Barrier Stays in Place
    • Reliable Barrier Adhesive
    View details
  • Coloplast Uro Two-Piece Urostomy Pouch, Drainable, Transparent, 6" Length, Micro 1 3/8" Stoma, Box of 10

    Regular price $4799
    Unit price$4.80/ea
    $4080 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    Very low stock (1 unit)
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Anti-Reflux Protection
    • Soft, Skin-Friendly Backing
    • Transparent for Easy Monitoring
    • Night Bag Compatible
    • Color-Coded Secure Fit
    View details
  • Hollister New Image Two-Piece Urostomy Pouch, Maxi, 9" LengthStoma, Transparent, Drainable, Non-Sterile

    Regular price $799
    Unit price$7.99/ea
    $680 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Ultra-Clear Odor-Barrier Film
    • Ceramide-Infused Skin Barrier
    • Anti-Reflux Protection
    • Color-Matched Secure Fit
    • Complete Pouch Change Kit
    View details
  • ConvaTec Natura Two-Piece Ostomy Pouch, Drainable, Transparent, 70mm Flange, 12", Box of 10

    Regular price $3499
    Unit price$3.50/ea
    $2975 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Audible Click for Secure Fit
    • Quick Snap-On, Snap-Off Design
    • Skin-Friendly, Barrier-Preserving Changes
    • Transparent for Easy Monitoring
    • Reliable Box of 10 Supply
    View details
  • Coloplast SenSura Flex Two-Piece Drainable Ostomy Pouch, Transparent, 11 1/2", Box of 20

    Regular price $8799
    Unit price$4.40/ea
    $7480 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    Low stock (7 units)
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Secure Two-Piece Adhesive Coupling
    • Flexible, Discreet Comfort
    • Independent Pouch Changes
    • 655-mL Drainable Capacity
    • Easy Color-Coded Matching
    View details
  • Coloplast SenSura Click Two-Piece Urostomy Pouch, Opaque, 10 3/8" Length, 40mm Maxi Stoma, Box of 10

    Regular price $4199
    Unit price$4.20/ea
    $3570 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    Very low stock (6 units)
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Anti-Reflux Protection
    • Soft Tuck-Away Outlet
    • Discreet, Splash-Reducing Design
    • 480-mL Capacity
    • Color-Coded for Easy Fitting
    View details
  • Coloplast SenSura Mio Flex EasiClose Two-Piece Ostomy Pouch, Drainable, Opaque, 11", Box of 10

    Regular price $3699
    Unit price$3.70/ea
    $3145 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Flexible, Body-Hugging Comfort
    • Full-Circle Anti-Ballooning Filter
    • Easy-Drain Wide Outlet
    • Convenient Inspection Window
    • Secure Maxi-Size Fit
    View details
  • Coloplast SenSura Mio Click Two-Piece Drainable Ostomy Pouch, Maxi, Box of 10

    Regular price $2799
    Unit price$2.80/ea
    $2380 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Elastic Adhesive for a Secure, Flexible Fit
    • Fast, Reliable Click Coupling
    • Red Color-Match for Easy Pairing
    • Extra-Capacity 655-mL Maxi Pouch
    • Available in 50mm & 60mm Sizes
    View details
  • ConvaTec Esteem Synergy+ Ostomy Pouch Two-Piece Drainable, Transparent, 12", Box of 10

    Regular price $4699
    Unit price$4.70/ea
    $3995 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    Very low stock (5 units)
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Secure Adhesive Coupling
    • Odor-Reducing Filter
    • Gentle Skin Protection
    • Easy-Drain Design
    • Clear Visual Monitoring
    View details
  • Coloplast SenSura Click Two-Piece Urostomy Pouch, Drainable Opaque with Red Coupling, 10 3/8" Length, 40mm Stoma, Box of 10

    Regular price $3499
    Unit price$3.50/ea
    $2975 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    Low stock (12 units)
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Reduces Risk of Urinary Infection
    • Comfortable Tuck-Away Outlet
    • Discreet, Flat Profile
    • Quieter, Splash-Reducing Design
    • Easy Color-Coded Coupling Match
    View details
  • Coloplast SenSura Mio Flex Ostomy Pouch, 2-Piece EasiClose Wide Outlet, Transparent, 2 3/4" Maxi, Box of 10

    Regular price $2799
    Unit price$2.80/ea
    $2380 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    In stock
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Clipless EasiClose Wide Outlet
    • Soft, Water-Resistant Comfort Layer
    • Flexible, Body-Contouring Fit
    • Easy Two-Piece Pouch Changes
    • Color-Coded for Accurate Sizing
    View details
  • Assura Original Two-Piece Drainable Ostomy Pouch with Filter, 60mm Flange, 11 1/2", Box of 10

    Regular price $3299
    Unit price$3.30/ea
    $2805 with AutoshipAutoship & save — 15% off your first Autoship order (up to $100 off), then 5% off every order after. Choose how often it ships, and skip, change, or cancel anytime.
    Very low stock (2 units)
    FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more
    • Skin-Friendly Adhesive
    • Built-In Odor Filter
    • Fast, Easy Emptying
    • Low-Profile Discretion
    • Durable Two-Piece Design
    View details

Two-Piece Ostomy Pouches

Two-piece ostomy pouches pair with a separate skin barrier (flange) so you can remove and replace the pouch without disturbing the barrier on your skin. This flexibility makes two-piece systems a favorite for people who empty frequently or want to switch between pouch styles. Shop trusted two-piece pouches from Hollister, Coloplast, and ConvaTec.

Why Choose a Two-Piece System

- Change the pouch without removing the skin barrier
- Less frequent barrier changes are gentler on the skin
- Swap between drainable, closed, or different lengths
- Easy to inspect and reposition

How to Choose

- Match the flange/coupling size of the pouch to your skin barrier - the two must be the same system and size to seal.

- Pick your pouch type - drainable for liquid/frequent output, closed for formed output, urostomy for urine.

- Choose with or without filter to manage gas and ballooning.

Frequently Asked Questions

Q: Will any pouch fit my barrier?
A: No - the pouch and barrier must be the same brand/system and the same flange size. Check the coupling size before ordering.

Q: Are two-piece pouches FSA/HSA eligible?
A: Yes.