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About this item

  • Up to 12 Hours of Overnight Protection
  • Maximum Absorbency
  • Unrivaled Comfort and Softness
  • Discreet, Underwear-Like Fit
  • Odor Control for Lasting Freshness

Depend Night Defense Overnight Underwear for Women

Depend  |  SKU: 51701-Pack
$24.99
$1.56/ea
FSA/HSA eligible Can be bought with an FSA/HSA card — no prescription or Letter of Medical Necessity needed. We keep this up to date, but always confirm eligibility with your health plan. Learn more

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Depend Night Defense Overnight Underwear for Women

Absorbency Level
4 drops - Heavy Absorbency
Heavy

 

Experience uninterrupted sleep and wake up feeling refreshed with Depend Night Defense Overnight Underwear for Women. Specifically engineered for nighttime use, these protective undergarments provide the heavy-duty absorbency required to manage overnight incontinence with total confidence. Unlike standard daytime products, Night Defense is designed with reinforced protection zones to handle the unique needs of side sleepers and those who shift throughout the night.

Constructed with a soft, cloth-like fabric, this underwear looks and feels like real lingerie, ensuring comfort without the bulk. The SureFit waistband helps keep the garment securely in place, while the form-fitting elastic strands provide a smooth, discreet fit under pajamas. Whether you are managing postpartum recovery or chronic bladder leakage, these overnight pull-ups offer the reliable barrier you need to protect your bedding and maintain your skin's health.

The advanced DryShield™ technology instantly captures moisture and locks away odors, providing a dry, irritation-free experience. By choosing Depend Night Defense, you are investing in a product that balances high-performance protection with the dignity and comfort you deserve. Rest easy knowing you have the ultimate defense against leaks, allowing you to focus on getting the quality sleep your body needs.

How does Night Defense differ from regular Depend Fit-Flex underwear?
Depend Night Defense is specifically designed with more absorbent materials and a reinforced core to handle larger volumes of fluid over a longer period, specifically optimized for lying down and sleeping.
Can these be worn during the day for heavy incontinence?
Yes. While they are optimized for overnight use, many users find the increased absorbency of Night Defense beneficial for long travel days or situations where frequent changes aren't possible.
Is the material noisy or "crinkly" when I move?
No. These are made with a quiet, breathable, cloth-like fabric designed to be silent and discreet, even if you toss and turn during the night.
How do I dispose of the used underwear?
Simply tear the side seams for easy removal, roll the garment up, and dispose of it in a waste bin. Do not flush this product down the toilet.
Are these scented to mask odors?
No, Depend Night Defense is fragrance-free and elemental chlorine-free, using a specialized core to neutralize odors naturally rather than masking them with perfumes.

Product Details

FSA/HSA Eligible Yes
Backing Type Cloth-Like
Absorbency Level Heavy
Gender Female
Style Pull-Up
Brand Depend
SKU Depend Night Defense Women

Key Features

  • Up to 12 hours of overnight protection for a restful, leak-free sleep.
  • DryShield™ technology instantly absorbs wetness and locks away odors.
  • Form-fitting elastic strands provide a smooth, discreet fit under sleepwear.
  • Reinforced core specifically shaped for feminine protection and side-sleeper safety.
  • Breathable, soft fabric stays cool and comfortable against the skin all night long.

Size Chart:

Size Small Medium Large X-Large
Style Pull Up Pull Up Pull Up Pull Up
Waist 24" to 30" 31" to 37" 38" to 44" 45" to 64"
Pant Size 00-8 8-16 16-20 20W+
Absorbency Overnight Overnight Overnight Overnight
Backing Cloth-Like Cloth-Like Cloth-Like Cloth-Like
Pack Qty 16 15 14 12
Case Qty 32 (2 packs) 30 (2 packs) 28 (2 packs) 24 (2 packs)
Color Beige Beige Beige Beige
SKU 47917 47918 45599 45591

Customers say

Customers praise the comfort, fit, and absorbency of the Depend Night Defense Overnight Underwear for Women. They appreciate the wide gusset, lack of noise, and extra absorbency for nighttime use. Fast shipping and great customer service are also highlighted.

AI generated from customer reviews

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Size Chart:

Size Small Medium Large X-Large
Style Pull Up Pull Up Pull Up Pull Up
Waist 24" to 30" 31" to 37" 38" to 44" 45" to 64"
Pant Size 00-8 8-16 16-20 20W+
Absorbency Overnight Overnight Overnight Overnight
Backing Cloth-Like Cloth-Like Cloth-Like Cloth-Like
Pack Qty 16 15 14 12
Case Qty 32 (2 packs) 30 (2 packs) 28 (2 packs) 24 (2 packs)
Color Beige Beige Beige Beige
SKU 47917 47918 45599 45591

Customer Reviews